RESUMEN

La criptococosis es una micosis oportunista causada por Cryptococcus neoformans, puede presentarse en personas sanas y en sujetos expuestos a palomas, pero los más frecuentemente afectados son los inmunocomprometidos. Se presenta el caso de una paciente de 43 años, que presentó un cuadro subagudo con síntomas respiratorios y neurológicos. Los datos clínicos y radiológicos revelaron una tumoración en hemitórax izquierdo, que fue compatible con un criptococoma, además de diseminación a SNC. Se descartó inmunocompromiso asociado. Se dio tratamiento completo por 10 semanas a base de anfotericina B, fluconazol y fluocitosina, sin embargo por persistir con la lesión a nivel de tórax y positividad para el microorganismo, se decide realizar resección de la lesión. Se continuó con antimicóticos y el resultado fue positivo con remisión de la sintomatología y títulos de antígeno negativos en LCR.

PALABRAS CLAVE

Cryptococcus neoformans, huésped inmunocompetente.

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