RESUMEN

Existe evidencia epidemiológica consistente que asocia, de manera independiente, la inhalación crónica de humo de biocombustibles con el desarrollo de tuberculosis pulmonar. Los mecanismos fisiopatológicos que subyacen dicha asociación son parcialmente conocidos. El humo de biocombustibles tiene diversos efectos a nivel del parénquima pulmonar y del sistema inmune innato los cuales, en su conjunto, podrían aumentar la susceptibilidad a diversas infecciones incluyendo Mycobacterium tuberculosis. En esta revisión describimos las características fisicoquímicas más importantes de las partículas presentes en el humo de biocombustibles y la forma en que éstas afectan algunos de los mecanismos inmunológicos que participan en la respuesta inmune contra Mycobacterium tuberculosis.

PALABRAS CLAVE

Biocombustible, enfermedad pulmonar, tuberculosis.

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