ABSTRACT

The avian influenza is caused by highly pathogenic virus A, transmitted from particularly farmer birds, pigs and poses a high risk for global public health. In humans the viral replication is prolonged, the virus could be detected in nasopharyngeal isolates for a median of 6.5 days, nasopharyngeal replication is less than in human influenza, and studies of low respiratory tract replication are needed. The initial symptoms in most patients have been high fever more than 38 °C, and influenza like illness with lower tract respiratory symptoms. Upper respiratory symptoms are present only sometimes. Also have been reported, diarrhea, vomiting, abdominal pain, pleuritic pain, and bleeding from the nose and gums have also been reported early in the course of illness. Commercial rapid antigen test are insensitive, and confirmatory diagnosis requires sophisticated laboratory support by an authorized World Health Authorized center.

KEYWORDS

Avian influenza, clinical features, outcome, laboratory findings, virologic diagnosis.

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