ABSTRACT

Non tuberculosis mycobacterium were described, after isolation of Mycobacterium tuberculosis by Koch, clinical significance wasn’t show until 1950 when were called atypical mycobacterium, based on in vitro characteristics. Nowadays had been described big series of patients HIV (+) and (-) with pulmonary and no pulmonary illness secondary to infection for atypical mycobacterium. Pulmonary illness secondary to NTM means a diagnostic and therapeutic challenge to the medical personal involved in the care of these patients. Evidence exist that prevalence of NTM like human pathogens had been increasing particularly in HIV (+) and patients with pulmonary pathology. In the United States of America the incidence of these NTM it found of 1.0-1.8 by 100,000 persons. Clinical manifestations more common are pulmonary, lymphatic, and in soft tissue, disseminated infection is possible too. In regard to these grow in incidence of illness secondary to infection of NTM, the American Thoracic Society (ATS) and the British Thoracic Society (BTS), developed and published guidelines sour diagnostic and treatment in this field.

KEYWORDS

Non tuberculosis mycobacterium, Chelonae mycobacterium, lung infection, diagnosis, treatment.

REFERENCES

1. Henry MT, Inamdar L, O’Riordain D, Schweiger M, Watson JP. Nontuberculosis mycobacteria in non-HIV patients: epidemiology, treatment and response. Eur Respir J 2004; 23: 741-746.

2. Griffith DE, Aksamit T, Brown-Elliot BA, Catanzaro A, Daley C. An official ATS/IDSA Statement: Diagnosis, treatment, and prevention of nontuberculosis mycobacterial disease. Am J Respir Crit Care Med 2007; 175: 367-416.

3. Subcommittee of the Joint Tuberculosis Committee of the British Thoracic Society. In: Campbell MD, Francis Drobniewski MD, Vaz Novelli MD, Peter Omerod MD, Anton Pozniak MD. Thorax 2000; 55: 210-218.

4. Wang HC, Liaw YS, Yang, Kuo PC, Luh KT. A pseudoepidemic of Mycobacterium chelonae infection caused by contamination of a fiberoptic bronchoscope suction channel. Eur Respir J 1995; 8: 1259-1262.

5. Master RN. Mycobacteriology. In: Isenberg HD Editor. Clinical Microbiology Procedures Handbook. Washington DC: ASM Pres;1st.1992: 3.12.9-3.12-10.

6. Vincent V, Brown BA, Jost KC Jr y Wallace RJ Jr. Mycobacterium: Phenotypic and Genotypic Identification. In: Murray PE, Baron E, Jorgensen J, Pfaller MA, Yolken RH Eds. Manual of Clinical Microbiology. 8th Ed. Washington DC: ASM Press; 2003: 560-584.

7. CT Findings in 14 patients with Mycobacterium chelonae pulmonary infection. Hazelton TR, Newell JD, Cook JL, Huitt GA, Lynch DA. AJR 2000; 175: 4.