Aspergillosis refers to the spectrum of disease caused by Aspergillus species. The aspergilloma is the most common and best-recognized form of pulmonary involvement due to Aspergillus; usually developing in a preformed lung cavity and the principal association is with Tuberculosis. The true incidence of aspergilloma is not known. Although frequently asymptomatic, the presence of a fungus ball due to Aspergillus may cause hemoptysis and in cases can be fatal, with a variable mortality ranging between 9 to 30%. Aspergilloma usually comes to clinical attention as an incidental finding, thus the diagnosis involve clinical and radiological findings confirmed by pathology. There is no consistent evidence that aspergilloma. Responds to antifungal agents, and these drugs rarely achieve the minimal inhibitory concentrations within the lung cavities. Surgical resection, despite a high morbidity, is the only proven therapy for these cases.
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