ABSTRACT

Background: Patients with advanced lung cancer show medical conditions and comorbidities which decreases the sleep quality and quality of life that could affect the oncological treatment response and the prognosis of patients. Objective: The proposal of this study was to investigate, in patients with advanced lung cancer, the prevalence of medical conditions and comorbidities that could be reverted before radiotherapy or chemotherapy treatment. Material and methods: Study design: baseline assessment of consecutive patients with diagnosed of non-small lung cancer stages III-A and III-B. To investigate the comorbidities we use PLATINO questionnaire (www.platino-alat.org/docs/cuestionario_ platino_ mexico.pdf). We applied also dyspnea scale MRC, the Pittsburgh sleep quality index (PSQI) and EuroQL. Lung function tests were spirometry, carbon monoxide diffusing capacity (DLCO) and gasometry (ATS/ERS 2005). PSQI and EuroQL scales were analyzed according authors criteria. Results: 46 patients were recruited; a) 32.6% of patients have a comorbid condition and 13.1% dyspnea; b) COPD prevalence was of 39.1% and 16.7% show hypoxemia; c) 50% reported a poor quality of sleep; d) the mean of quality of life score was high (0.848 [SE ± 0.185]); 45.7% refer pain and 19.6% anxiety and depression symptoms; e) sleep quality was significantly associated with pain and anxiety and depression symptoms. Conclusions: There are comorbidities and medical conditions in advanced lung cancer patients that could be treated before the radio and chemotherapy to improve the prognosis.

KEYWORDS

Lung cancer, lung function, quality of life, sleep.

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