NCT
INICIO RECIENTES ARCHIVO COVID-19
INICIO RECIENTES ARCHIVO PUBLICAR INSTRUCCIONES
PARA AUTORES COVID-19 ENTRAR / REGISTRARSE HISTORIA NOSOTROS DIRECTORIO CONTACTO
Anhidrasa carbónica, nuevas perspectivas

Lorena Espinosa Monroy , Martha Patricia Sierra Vargas





2010, Número 4

2010; 69 (4)






RESUMEN

La anhidrasa carbónica es una metaloenzima zinc dependiente, juega un papel importante en la catálisis reversible de la hidratación del CO2 para formar HCO3- y H+. De las cinco familias descritas, la AC-α se encuentra en los seres humanos, ésta se divide en cuatro subgrupos y catorce isoformas. Su amplia distribución celular, le confiere una versátil funcionalidad. Los estudios reportados recientemente nos llevan a cuestionarnos acerca del papel que esta enzima juega en la génesis, el control y progreso de las enfermedades pulmonares, como asma, EPOC e inclusive la aterosclerosis y cáncer.

PALABRAS CLAVE

Anhidrasa carbónica, dióxido de carbono, bicarbonato, enfermedades pulmonares.

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2010, Número 4

2010; 69 (4)