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SARS-CoV-2: a bibliographic review of the most relevant topics and evolution of medical knowledge about the disease

Vargas-Lara, Ana Karina; Schreiber-Vellnagel, Viviane; Ochoa-Hein, Eric; López-Ávila, Alberto





2020, Number 3

2020; 79 (3)






ABSTRACT

Since December 2019 the world has been affected by a pandemic caused by the SARS-CoV-2 virus, which belongs to the β-coronavirus family. This group of viruses are known for their great infectious capacity, rapid transmission and clinical manifestation as a respiratory syndrome, which has caused the death of more than 300,000 people worldwide. This document was written from March to May 2020 in order to report of the most relevant issues of the disease; historical background, viral morphology, pathophysiology, transmission, clinical manifestations, clinical characteristics of infected patients and asymptomatic patients, incubation period, diagnostic tests, expected results in laboratory and imaging tests, main complications of infection, status of vaccine development and the use of convalescent plasma in treatment, development of a vaccine, prevention and personal care to avoid infection and, at last, possible reinfection. In addition, this article compares and verifies the information between various articles on each subtopic, to have a broad and complete perspective of the different results, findings and opinions about COVID-19.

KEYWORDS

2019-nCoV, coronavirus, COVID-19, review, SARS-CoV-2.

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2020, Number 3

2020; 79 (3)