Paraquat poisoning in pediatrics and its impact on severe lung damage: a case report

Paraquat poisoning in pediatrics and its impact on severe lung damage: a case report

Gissel A. Burbano-Andrade 1 , Paola C. Garrote-Bernal 1, 2 , Thamara León-López 1, 2 , Juan P. Rojas-Torres 1

1 Centro de Cuidados Cardioneurovasculares Pabón, Nariño, Colombia; 2 Fundación Universitaria San Martín, Nariño, Colombia

*Correspondence: Gissel A. Burbano-Andrade. Email: gissel970317@gmail.com

Abstract

Introduction: Paraquat is an extremely toxic herbicide that can cause pulmonary fibrosis and severe respiratory damage. Case report: This case report presents a 17-year-old male patient from Orito, Putumayo, who was admitted to a tertiary care center in Pasto, Nariño, after ingesting 100 ml of paraquat in a suicide attempt. He presented with dysphagia, odynophagia, diaphoresis, and hemodynamic instability. Although the initial chest X-rays showed no abnormalities, subsequent studies revealed progressive lung damage. A chest computed tomography scan confirmed severe pulmonary injury. The patient experienced worsening gas exchange, severe hypoxemia, and acute kidney failure, requiring hemodialysis. Due to a poor clinical course despite established treatment, he became a candidate for lung transplantation. Conclusion: This case highlights the rapid progression and severity of paraquat-induced pulmonary fibrosis in young patients, emphasizing the need for early medical intervention to anticipate complications and improve survival chances.

Keywords: Lung damage. Pulmonary fibrosis. Herbicides. Paraquat. Oxidative stress.

Contents

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